Aspidospermatan-aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis.

نویسندگان

  • Chew-Yan Gan
  • Yun-Yee Low
  • Ward T Robinson
  • Kanki Komiyama
  • Toh-Seok Kam
چکیده

Leucofoline and leuconoline, representing the first members of the aspidospermatan-aspidospermatan and eburnane-sarpagine subclasses of the bisindole alkaloids, respectively, were isolated from the Malayan Leuconotis griffithii. The structures of these bisindole alkaloids were established using NMR and MS analysis, and in the case of leuconoline, confirmed by X-ray diffraction analysis. Both alkaloids showed weak cytotoxicity towards human KB cells.

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عنوان ژورنال:
  • Phytochemistry

دوره 71 11-12  شماره 

صفحات  -

تاریخ انتشار 2010